In my experience, when the prescriptions don't match, I don't need to call the patient. It's when I write for Zyrtec and the pharmacy correctly changes it to cetirizine. When it is sent for refill, it says Cetirizine 10 mg. Take one daily. #30. And, it is matched against my record of Zyrtec 10 mg.....Since it is always going to be their version unless I change it to Dispense As Written, I click on the med and change them so they match. They will then match each time. Or it can be how they write the sig.