Dr. Lee,
DMPE (1) uses the Ver. 11 NaturallySpeaking speech engine and DMPE 2 (the latest version) uses the Ver. 12 speech engine. Depending on which Ver. 10 application you are using, it was either called the Small Practice Edition or Medical 10. Are you certain that you have a Medical 10 5 user license? The reason why I am asking is because most end-users purchase a single user full box copy of Medical 10 which sold for about $1100 - $1500 (depending on if you purchased Small Practice or Medical 10). The 5 user edition probably cost something in the vicinity of about $7000. If you actually do have 5 users that need upgrading, as opposed to 1, I would recommend purchasing the DMPE 2 Upgrade at
http://www.knowbrainer.com/NewStore/pc/viewPrd.asp?idproduct=467&idcategory=71 because it would be your least expensive option. This introductory pricing will remain in place through September. We are also including a complementary pictorial installation and training guide that will show you how to properly upgrade your previous user profile. Note that this version of DMPE 2 is licensed to the individual user but can be installed (activated) on up to 4 computers. Amazon resellers are not only not offering a better deal but they?re not including virtual onsite support, training or a step-by-step upgrade guide.