As an addendum to Bert's comment about PDF markup. All of you Fujitsu ScanSnap S1500/fi-6130 users should already have a copy of Acrobat Standard. It's worth $300 so it'd be a mistake not to use it. Considering the S1500 is about $400, you're really paying a 100 bucks for the scanner. It's a pretty damn good deal.

Here's the comparison between Pro and Standard: https://www.adobe.com/products/acrobat/matrix.html

Here's a condensed comparison: http://www.softwaremedia.com/acrobat_standard_vs_professional_difference.html

In my opinion, the Standard should be more than enough. If you're considering getting it, think about getting a document scanner while you're at it because it'll probably be way cheaper as a bundle.