I have found ads placed in material which I am reading to be especially annoying. I'm sure they register me as clicking on them, but its by mistake. Its why I stopped using Yahoo email and went to Google mail. Now G-mail is putting in some ads and I of course find it very annoying.
I would really hate for the specialized software tool that i use each day to display the never-to-be-sufficiently-darned ads as I'm trying to work.