I am not sure we are talking about the same thing, but my method for updating my AmazingMeds.mdb database is to update it on the fly anytime I find myself prescribing a medication which is not in it. Alternatively, keep a running list (like with OneNote -- one of the better Microsoft programs) and update it monthly. Yearly? Hell, Vioxx (sp?) could be in there 11 months after it was taken off the market.