It is pretty much the same for the same things you use.
I like eprescribing, it was the main reason to jump.
It isn't a whole lot slower on startup, and usually I keep it up and running so that is not a big deal. It interfaces and runs at about the same speed as V4.
Wait for it to go final, maybe even a version after, but it is good. I think it was worth the hassle of upgrading (no more so than most major upgrades), especially for eprescribing.
