I am the Network Admin/IT Guy for our medical practice with a couple of docs. We currently run the database on the server and have version 4.0.45. We use XP Pro on all the desktops and although I wasn't here when it was all set up things are running very smoothly thus far. I have not tried the synch because I had read in a post in January that it wasn't working correctly. I will be testing it this week though because we are going to need to do something like that for a provider that will be going out of town to see clients in an educational setting.