PaperPort seems to be on its way out. Our office has been using it for about 13 years, this is what our staff is used to using for scanning, and I am not ready to give up on it yet.
Apparently the only version which is Windows 10 compatible is PaperPort 14.5. It appears that retail versions are still 14.0. However, this article
Yes, I am a Paperport devotee, a student of Leslie.
I use a special version of PP, Paperport SE, which comes free with Brother multifunction machines. I just checked, and new machines are still coming with it. Yay, I will never give it up!