Todd are you a family doc? If you are I can tell you about a resource that might help. PM me.
We looked at Praxis very seriously. It is a really cool program.
From another message board I connected with a long time user who said support is a big problem. Praxis does the updating by logging into your server. During an update, they deleted a lot of her imported items and her labs. She had to have her staff fax items back into the chart.