A few months ago, I started Uloric on a lady who developed a fixed drug eruption shortly after starting allopurinol. She has been fine on the Uloric. Both worked really well for lowering the uric acid level. My main fear about allopurinol is the potential for Stevens Johnson syndrome, which I have seen in a patient (due to another cause) and I don't ever want to see again! I know a lot of other things can cause it, too, though. I have also seen bone marrow suppression from allopurinol twice, but caught it because I watch for it.
