Currently, I'm printing scripts on plain paper (no problems so far here in Louisiana...) and still hand-signing them.
I now use acrobat to do all of my refills, though - we ask patients who call in for refills to instead have their pharmacy fax us a request. It gets dumped onto my desktop as a PDF and then I use acrobat to sign and fax back. Takes my nurse out of the loop completely, so she can concentrate on importing scanned stuff

Jim