Bert,
Unfortunately Quickbook 2006 doesn't run with Vista, even in XP compatibility mode. I called Intuit, they said, 2006 payroll function is not compatible with Vista, must update to Quickbook 2007.
You are right, there are Brother drivers for Vista, and it is possible to buy extra RAM, but it sounds like lots of extra work for what purpose? Would it increase my collections? Or make my work easier? If not, I better wait...