Plant a dedicated beefy server computer in some hidden corner of one of the exam rooms (since the waiting room is probably a bad idea) that will not be used as a work station at all. Have two workstation computers on the office wireless network. Wife uses one to see patients and I remotely log into second workstation to take care of front office business. When wife is on a house call (presumably after-hours anyway) she accesses #2 workstation remotely from the laptop she usually uses as #1 workstation while I enjoy a break from front office duties. I can't imagine not having access to AC and e-prescribing while on a house call and I definitely want to avoid any sync difficulties.
That about sums it up. You could also tweak workstation #2 so you can both work on it remotely simultaneously, if necessary. I'm glad you decided to have a dedicated server/main computer. Reduces a lot of IT headache. That's good that you already have a 4G hotspot. You should try to get a fixed line (Cable/FiOS/DSL, if possible) at the office if you plan on continuous remote access.