I am not sure your question is clear to me. Are you trying to add or remove a medicine in a current encounter or, say, one you have changed outside of an encounter? If it is outside of an encounter, highlight the patient's name, right click and scroll to "medications and eprescribing". You can add a medicine there or you can inactivate one there. If you want to add it but not actually refill it at that time, go through the screens until it says "transmit", "print" or close. close the screen and the medication will not be sent anywhere but will show up in their list. If you want to remove a medication, highlight it in their list, click the "inactivate" tab below the list of meds and then complete the info as to why it is being inactivated. It should now be removed from the list. The next time you open a chart to start an encounter the added or removed meds should be evident.