For those having networking issues with ePrescribe and II opening, you can try the following using an elevated command prompt to change unnecessary settings on your network card:
Disable Receive-Side Scaling
netsh int tcp set global rss=disabled
Disable Task Offload
netsh int ip set global taskoffload=disabled
Disable Add-On Congestion Control Provider
netsch int ip set global congestion=none
Disable QoS
Go to NIC card properties -> Advanced -> Settings -> QoS (delete)