I will comment on the type of processor. I have machines with AMD and Intel. If it's the same type of processor, the difference is nothing. BUT, make sure you get a DUO (or DUAL) processor. Huge difference in speed. Fortunately most of the newer desktops have the duo processors at a minimum (plus, they're 64bit compatible).
Also, if you go with Windows 7 (which I have used for some time now and really have liked it), make sure to get at least 4GB of RAM and go with the 64bit Windows 7 (I think they all come with 64 bit now on the new computers). You may even want to go to 8GB or more if you're a speed freak like me. If you go with 32bit Windows 7, you can only use 3.3GB of RAM, max. Keep a desktop for 6 years and a 32 bit system with 3GB of usable RAM will drive you crazy in 3 years.
I will say the only negative to 64bit Windows 7 is compatibility with ancient hardware. Say that 1998 scanner that your office manager still uses every once in a while. Well, that thing may or may not work due to the availability of updated 64bit drivers. I personally haven't found anything that wouldn't work but I don't have a lot of super old stuff. I do have an old HP all-in-one that I've hung on to for about 7 years and it works fine.
I like refurbished stuff too. Much cheaper and just as good in my experience.
Last edited by scalpel; 01/14/2010 10:55 PM.