@Leslie I forgot you are using Backup Assist. The new version is awesome. I haven't gone to it yet, though. It has an automatic FTP, that can back up offline.
@David Again, to be fair, I don't use AC's backup much on V4. But, in my testing, if you check the box to include imported items, it should back up your imported files and data files. When I say data files I mean basically your databases such as AmazingCharts.mdf, etc. While there may be enough room eventually to back up EVERYTHING offsite, I still think it would be very timely unless you have tremendous bandwidth. The thing I don't like about AC's offsite backup compared to Mozy or iBackup or the other 20 commercial sites, is it is pricier, you can't see your backups and download them to test them without making a test AC program, and it doesn't have nearly the same options as commercial backups such as storage, etc.
BUT, you can set it to back up Imported Items and your Databases and back everything up locally like to an external hard drive.
Backup Assist uses the native NTBackup program that comes with Windows although the newest version is switching to imaging. Imaging is the way to go. But, Backup Assist is reasonable and has many, many features and gives an incredibly detailed report.
If you need another recommendation, Acronis is rock solid. It is an imaging program. Basically, it is an exact snapshot of your computer. It is very easy to browse through it and look at files as if they were the exact ones on your PC.
And, as we all talk about Servers vs non-servers, one big advantage of most Microsoft Server OS is the VSS. I won't go into that, but it makes auto versions of shared folders so that any file in AC is backed up constantly at certain time intervals.
Finally, as far as backing up offsite and trying to back up your Imported Items, why not back up the databases daily (they are mission critical), and only back up the imported items weekly. Not so mission critical.