Alexis,
Hi. Once you set up your formatting (4 by 6) and the "twips" in the admin section, you can print anything that you would normally print on 8 1/2 by 11 paper. So, if you can do a digital signature on your regular script, then you can on this as well.
I am not sure what paper you will be using. We only use the TSP800 for printing controlled scripts and use tamper proof paper, so obviously, I have to actually sign the script anyway. If you were printing to plain paper, then you may not need to, but I tend to sign all my hard copy scripts anyway where I don't sign my faxed scripts.
I hope this helps. Let me know if I misunderstood your question.
